Bernadette is a frightfully intelligent wife and mother whose intense allergy to Seattle specifically, and to people in general, has driven her to hire a virtual assistant in India to execute even her most basic tasks. Then her daughter, Bee, insists on a family trip to Antarctica as her reward for getting perfect grades in middle school, and Bernadette is faced with the daunting prospect of actual human interaction. And then Bernadette disappears....

Robert Langdon, Harvard professor of symbology and religious iconology, arrives at the Guggenheim Museum Bilbao to attend the unveiling of a discovery that "will change the face of science forever". The evening's host is his friend and former student, Edmond Kirsch, a forty-year-old tech magnate whose dazzling inventions and audacious predictions have made him a controversial figure around the world. This evening is to be no exception: he claims he...